Severe Hypokalaemia, Hypertension, and Intestinal Perforation in Ectopic Adrenocorticotropic Hormone Syndrome
Published: January 1, 2016 | DOI: https://doi.org/10.7860/JCDR/2016/.7127
Tezcan Kaya, Cengiz Karacaer, Seyyid Bilal Açikgöz, Yusuf Aydemir, Ali Tamer
1. Assistant Professor, Department of Internal Medicine, Sakarya University Faculty of Medicine, Sakarya, Turkey.
2. Medical Doctor, Internal Medicine Specialist, Department of Internal Medicine, Sakarya University Training and Research Hospital, Sakarya, Turkey.
3. Medical Doctor, Research Assistant, Department of Internal Medicine, Sakarya University Faculty of Medicine, Sakarya, Turkey.
4. Assistant Professor, Department of Chest Diseases, Sakarya University Faculty of Medicine, Sakarya, Turkey.
5. Professor, Department of Internal Medicine, Sakarya University Faculty of Medicine, Sakarya, Turkey.
Correspondence
Dr. Tezcan Kaya,
Sakarya University Faculty of Medicine, Department of Internal Medicine-54100, Sakarya,Turkey.
E-mail: tezcankaya@gmail.com
Ectopic adrenocorticotropic hormone (ACTH) syndrome is a rare cause of the Cushing’s syndrome. The occurrence of the ectopic ACTH syndrome presenting with severe hypokalaemia, metabolic alkalosis, and hypertension has been highlighted in case reports. However, presentation with lower gastrointestinal perforation is not known. We report the case of a 70-year-old male patient with severe hypokalaemia, metabolic alkalosis, hypertension, and colonic perforation as manifestations of an ACTH-secreting small cell lung carcinoma. Ectopic ACTH syndrome should be kept in mind as a cause of hypokalaemia, hypertension, and intestinal perforation in patients with lung carcinoma.
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